Diseases of the spine and joints are becoming an increasingly urgent problem in modern society. In many ways this contributes to the image and conditions of life, malnutrition, intoxication and stress. The main symptoms of joint diseases are composed of pain, feelings of stiffness, rapid fatigue, stiffness, deformities and crunch. All this, to a large extent, reduces the quality of human life and can lead to the need for surgical intervention and disability.
If earlier it was believed that degenerative joint diseases, the prerogative of elderly people, now osteochondrosis and complications associated with it are significantly "younger".
Among the examined (15,405 representatives of the population over the age of 18), 47.5% had compression or reflex syndromes of lumbar or cervical osteochondrosis, more often lumbar. In 4% there was a combination of cervical and lumbar osteochondrosis syndromes. There is a direct positive dependence of the frequency of clinical manifestations of osteochondrosis of the spine on age: so, at the age of 20 years, the syndromes of osteochondrosis were revealed in 5.7%, 21-30 years - in 17% of the examined, 31-40 in 48%, 41 -50 years - in 71%, 51-60 years - in 74%, and in persons over 60 years - in 80% of cases.
Thus, degenerative-dystrophic diseases of the joints and spine are common diseases and are of great practical importance, their frequency increases with age.
Joint pathologies can be primary (starting without a noticeable cause) and secondary (develop at any age due to trauma, vascular disorders, static anomalies, arthritis, aseptic bone necrosis, congenital dysplasia, etc.).
Cartilaginous tissue consists of cells of chondrocytes and intercellular substance, which make up fibers and matrix. The main component of the extracellular matrix is chondroitin sulfate, it plays an important role in maintaining the structural integrity of the tissue. As part of the Aggrecan, chondroitin sulfate is the main component of the cartilage. Densely packed and highly charged sulfate groups of chondroitin sulfate generate an electrostatic repulsion, which provides the most part of the resistance to cartilage compression. The loss of chondroitin sulfate in cartilage is the main cause of osteoarthritis.
At present, it is believed that degenerative-dystrophic joint diseases are associated with local deficiency or degradation of natural substances, including internal chondroitin sulfate.
Chondroitin sulfate has an anti-inflammatory effect, stimulates the synthesis of proteoglycans and hyaluronic acid, reduces the catabolic activity of chondrocytes, inhibits the synthesis of proteolytic enzymes, nitric oxide and other substances that contribute to damage to the cartilage and cause apoptosis of the articular chondrocytes.
The drug "Regenart", developed by the NPCRIZ, contains highly active biologically available form of chondroitin sulfate, which is rapidly absorbed in the gastrointestinal tract and enters the injured joints, activating the process of their recovery.
In addition, the drug Regenart contains dihydroquercetin (DHA), a flavonoid derived from larch Siberian wood (Larix sibirica Ledeb.) And larch dahurian (Larix dahurica Turcz.). Its pharmacological action is anti-edema, antioxidant, detoxifying, capillaroprotective.
DHA inhibits the processes of lipid peroxidation of cell membranes, prevents the damaging effect of free radicals, inhibits premature aging of cells and the development of various diseases.
One of the characteristic features of dihydroquercetin is its great antioxidant activity, due to which this substance successfully fights free radicals. DHA is able to regulate the processes of metabolism at the level of cell membranes and has a strong anti-allergic and anti-inflammatory effect.
Dihydroquercetin improves cartilage, bone and connective tissue, strengthens small and large blood vessels, and also lowers triglycerides and cholesterol in the blood, preventing the formation of blood clots. The substance protects the stomach and liver from harmful effects, stimulating the restoration of the mucous membrane of the stomach and duodenum. Even a small amount of dihydroquercetin in the usual diet is able to provide effective prevention of various diseases, including tumors and musculoskeletal.
The composition of the drug Regenart also includes the root of a dandelion and an artichoke.
A feature of dandelion roots is the ability to accumulate trace elements from the soil. Due to the calcium content, dandelion roots are recommended to be used as part of complex therapy in the treatment of osteoporosis and brittle nails. And such microelements as copper, manganese and selenium potentiate the synthesis of various forms of the most important antioxidant enzyme, superoxide dismutase (SOD). Glycosides (taraxacin, taraxacerin), stimulate the proliferation of chondrocytes in the cartilaginous tissue, which allows to change the state of the cartilage matrix.
Vitamins A, B and C groups help improve the synthetic and energy function of chondrocytes.
Artichoke extract is known as a powerful detoxifier, used for diseases of the liver, gastrointestinal tract, genitourinary system. The natural preparation is indispensable for people exposed to the harmful effects of the environment.
Artichoke extract helps to destroy toxins, regenerate the liver, relieve the pain syndrome in the joints. It has good choleretic and diuretic properties, promotes the release of degradation products. Normalization of metabolic processes is facilitated by the ascorbic acid, carotene, vitamins B1 and B2, rutin, inulin contained in the artichoke field.
No less important task of the drug is the restoration of the functional activity of the liver. By the way, inflammatory diseases of the joints, which torment many people, are directly related to liver health. The fact is that the liver is an organ that can be considered as a laboratory responsible for metabolic processes. It is for this reason that any disruption of the functioning of the liver adversely affects the condition of the cartilage tissue. Improved liver function contributes to the regenerative capacity of cartilage tissue.
Thus, all components of the drug "Regenart" have a complex effect on the restoration of joints, relieve inflammation, reduce pain syndrome. The drug is recommended both at different stages of development of the pathological process, and for the prevention of joint damage. Of course, prevention is the most beneficial method of maintaining health and active longevity.